Respiratory Disease in Practice

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Investigation and treatment of severe chronic obstructive pulmonary disease
RDIP, Volume 21, Number 1.

Patients with severe chronic obstructive pulmonary disease (COPD) have distressing symptoms, significant exercise limitation, reduced quality of life and a poor prognosis. What is less clear is how to define severe COPD, largely as a result of its multisystem nature and the heterogeneity of its clinical presentation.

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