Respiratory Disease in Practice

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New approaches to future treatments for cystic fibrosis
RDIP, Volume 17, Number 4.

The identification of the cystic fibrosis (CF) gene sequence in 1989 resulted in an explosion of molecular and cellular research. This has led to a dramatic improvement in our understanding of the pathophysiology of CF and the development of exciting new therapeutic options to combat this disease. Although significant improvements in early diagnosis and conventional therapy have increased life expectancy to a median of 30 years, most patients still die from respiratory failure in early adulthood.1

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